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Excessive amounts of body fat, especially stored in and around the abdomen, release adipokines. These mediators are known as cytokines or adipokines (ones from fat)

These are a broad category of proteins secreted by one cell and then affecting other cells (through a signaling cascade).  Many adipokines increase inflammation in our body.  Others impact cells producing different cytokines and lead to  a cascade of signals causing insulin resistance, auto-immune disease, osteoarthritis, vascular disease, cancers, premature aging and death.

Cancers risks associated with Obesity include:

Bladder, Brain, Breast, Cervical, Colon, Uterine, Esophageal,

Gallbladder, Head & Neck, Kidney, Leukemia, Liver, Multiple Myeloma

Non-Hodgkin’s Lymphoma, Ovarian, Prostate, Pancreatic, Stomach, and Thyroid.

More fat cells = more adipokines = more damage.

Lowering your percent body fat is vital to lifelong health.

For further information or further understanding of these factors here are a couple of links